Basic Information
ID: ALA2034136
Type: Binding
Description: Inhibition of 5-lipoxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 mins measured after 10 mins by HPLC analysis
Organism: Homo sapiens
Cell type: PMNL
Activity Charts
Bioactivity
Activity Types for Assay ALA2034136
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 283.33 | 3.73 | 3.73 |
| 325.39 | 3.76 | 3.76 |
| 310.38 | 3.34 | 3.34 |
| 309.39 | 4.06 | 4.06 |
| 329.81 | 4.41 | 4.41 |
| 353.44 | 4.55 | 4.55 |
| 374.26 | 4.52 | 4.52 |
| 313.35 | 3.90 | 3.90 |
| 329.81 | 4.41 | 4.41 |
| 329.81 | 4.41 | 4.41 |
| 399.47 | 4.99 | 4.99 |
| 356.36 | 3.37 | 3.37 |
| 472.61 | 5.91 | 5.91 |
| 366.44 | 4.10 | 4.10 |
| 442.54 | 5.33 | 5.33 |
| 345.42 | 4.91 | 4.91 |
| 361.42 | 4.62 | 4.62 |
| 357.86 | 5.19 | 5.19 |
| 391.88 | 6.19 | 6.19 |
| 391.88 | 6.19 | 6.19 |
| 405.91 | 5.98 | 5.98 |
| 379.87 | 5.56 | 5.56 |
| 379.87 | 5.56 | 5.56 |
| 353.44 | 4.55 | 4.55 |
| 375.45 | 4.92 | 4.92 |
| 345.42 | 4.91 | 4.91 |
| 334.40 | 4.24 | 4.24 |
| 407.49 | 6.69 | 6.69 |
| 449.53 | 7.33 | 7.33 |
| 437.52 | 6.70 | 6.70 |
| 407.49 | 6.69 | 6.69 |
| 395.48 | 6.06 | 6.06 |
| 354.43 | 5.38 | 5.38 |
| 323.42 | 4.45 | 4.45 |
| 324.41 | 3.73 | 3.73 |