Assay Report Card

Basic Information

ID: ALA2034296

Type: Binding

Description: Enhancement of human BSEP E297G mutant trafficking to cell membrane in MDCK2 cells co-expressing NTCP assessed as accumulation of [3H]taurocholate at 1 uM preincubated for 24 hrs prior incubation with [3H]taurocholate measured after 2 hrs by liquid scintillation counting

Organism: Homo sapiens

Cell type: MDCK-II

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
615.949.159.15