Assay Report Card

Basic Information

ID: ALA2034332

Type: Functional

Description: Ex-vivo inhibition of PrCP in heat inactivated 100% plasma of C57 mouse assessed as target engagement calculated as [cmpd]plasma/([cmpd]plasma + Ki (heat inactivated plasma))x100 at 30 mg/kg, po after 20 hrs by FRET analysis

Organism: Mus musculus

Strain: C57

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
575.536.996.99
531.025.875.87
517.005.565.56