Assay Report Card

Basic Information

ID: ALA2034336

Type: Functional

Description: Ex-vivo inhibition of PrCP in heat inactivated 100% plasma of C57 mouse assessed as efficacy index calculated as ratio of [cmpd]plasma to (%free fraction)/(dose x mouse IC50) at 10 mg/kg, po after 20 hrs by FRET analysis

Organism: Mus musculus

Strain: C57

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
531.025.875.87
545.056.166.16
517.005.565.56