Basic Information
ID: ALA2038473
Type: Functional
Description: Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysis
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2038473
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.34 | 3.48 | 3.48 |
| 371.31 | 3.14 | 3.14 |
| 399.37 | 3.87 | 3.87 |
| 399.37 | 3.87 | 3.87 |
| 399.37 | 3.87 | 3.87 |
| 461.44 | 5.06 | 5.06 |
| 425.40 | 4.26 | 4.26 |
| 475.46 | 5.10 | 5.10 |
| 489.49 | 5.49 | 5.49 |
| 411.38 | 4.02 | 4.02 |
| 413.39 | 4.26 | 4.26 |
| 394.92 | 3.50 | 3.50 |
| 444.93 | 4.38 | 4.38 |
| 444.93 | 4.38 | 4.38 |
| 390.96 | 3.67 | 3.67 |
| 376.93 | 3.36 | 3.36 |
| 376.93 | 3.36 | 3.36 |
| 421.38 | 3.47 | 3.47 |
| 372.51 | 2.72 | 2.72 |
| 410.48 | 3.73 | 3.73 |
| 410.48 | 3.73 | 3.73 |
| 367.50 | 2.58 | 2.58 |
| 367.50 | 2.58 | 2.58 |
| 376.93 | 3.36 | 3.36 |
| 420.58 | 2.11 | 2.11 |
| 342.49 | 2.71 | 2.71 |
| 401.34 | 2.86 | 2.86 |
| 413.35 | 3.01 | 3.01 |
| 415.37 | 3.25 | 3.25 |
| 400.35 | 2.44 | 2.44 |
| 414.38 | 2.83 | 2.83 |
| 413.35 | 3.40 | 3.40 |
| 415.32 | 2.39 | 2.39 |
| 414.34 | 1.96 | 1.96 |
| 426.35 | 2.11 | 2.11 |
| 428.36 | 2.35 | 2.35 |
| 400.31 | 1.57 | 1.57 |
| 414.34 | 1.92 | 1.92 |