Basic Information
ID: ALA2040233
Type: Binding
Description: Inhibition of FLAP in A23187-stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 10 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2040233
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 283.33 | 3.73 | 3.73 |
| 505.09 | 7.23 | 7.23 |
| 545.92 | 7.92 | 7.92 |
| 436.63 | 5.40 | 5.40 |
| 479.29 | 7.35 | 7.35 |
| 485.37 | 6.66 | 6.66 |
| 462.37 | 5.26 | 5.26 |
| 402.97 | 7.09 | 7.09 |
| 405.88 | 6.56 | 6.56 |
| 368.52 | 6.43 | 6.43 |
| 402.97 | 7.09 | 7.09 |
| 447.42 | 7.20 | 7.20 |
| 386.51 | 6.57 | 6.57 |
| 494.42 | 7.04 | 7.04 |
| 436.52 | 7.45 | 7.45 |
| 393.53 | 6.31 | 6.31 |
| 382.55 | 6.74 | 6.74 |
| 398.55 | 6.44 | 6.44 |
| 410.61 | 7.56 | 7.56 |
| 424.63 | 7.73 | 7.73 |
| 426.56 | 6.22 | 6.22 |
| 382.55 | 6.74 | 6.74 |
| 386.51 | 6.57 | 6.57 |
| 393.53 | 6.31 | 6.31 |
| 384.52 | 6.14 | 6.14 |
| 426.56 | 6.36 | 6.36 |
| 398.55 | 6.44 | 6.44 |
| 436.52 | 7.45 | 7.45 |
| 386.51 | 6.57 | 6.57 |
| 393.53 | 6.31 | 6.31 |
| 426.56 | 6.22 | 6.22 |
| 437.41 | 7.74 | 7.74 |
| 437.41 | 7.74 | 7.74 |
| 456.63 | 7.23 | 7.23 |
| 458.60 | 6.46 | 6.46 |
| 369.51 | 5.83 | 5.83 |
| 369.51 | 5.83 | 5.83 |
| 369.51 | 5.83 | 5.83 |
| 419.57 | 6.98 | 6.98 |
| 416.95 | 6.73 | 6.73 |
| 382.51 | 6.08 | 6.08 |
| 416.95 | 6.73 | 6.73 |
| 440.54 | 6.00 | 6.00 |
| 336.44 | 4.47 | 4.47 |
| 388.94 | 6.53 | 6.53 |
| 350.46 | 4.56 | 4.56 |
| 417.00 | 7.26 | 7.26 |
| 360.89 | 6.20 | 6.20 |
| 450.97 | 7.12 | 7.12 |
| 433.00 | 7.10 | 7.10 |
| 418.97 | 6.79 | 6.79 |
| 510.08 | 8.06 | 8.06 |
| 560.14 | 9.22 | 9.22 |
| 402.97 | 7.09 | 7.09 |
| 437.41 | 7.74 | 7.74 |