Basic Information
ID: ALA2040539
Type: Binding
Description: Inhibition of MK2 in human THP1 cells assessed as inhibition of LPS-induced HSP27 Ser78 phosphorylation incubated for 60 mins prior to LPS-induction measured after 60 mins
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2040539
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.98 | 5.25 | 5.25 |
| 405.89 | 5.33 | 5.33 |
| 405.89 | 5.33 | 5.33 |
| 422.87 | 3.82 | 3.82 |
| 484.99 | 5.91 | 5.91 |
| 484.99 | 5.91 | 5.91 |
| 413.48 | 3.43 | 3.43 |
| 436.94 | 4.60 | 4.60 |
| 485.98 | 5.30 | 5.30 |
| 485.98 | 5.30 | 5.30 |
| 485.98 | 5.30 | 5.30 |
| 503.97 | 5.44 | 5.44 |
| 486.96 | 4.70 | 4.70 |
| 486.96 | 4.70 | 4.70 |
| 502.98 | 6.05 | 6.05 |
| 520.97 | 6.19 | 6.19 |
| 520.97 | 6.19 | 6.19 |
| 474.95 | 4.63 | 4.63 |
| 563.06 | 6.36 | 6.36 |
| 563.06 | 6.36 | 6.36 |
| 563.06 | 6.36 | 6.36 |
| 563.06 | 6.36 | 6.36 |
| 563.06 | 6.36 | 6.36 |
| 562.07 | 6.97 | 6.97 |
| 561.09 | 7.57 | 7.57 |
| 563.06 | 6.36 | 6.36 |
| 546.61 | 5.85 | 5.85 |
| 597.51 | 7.02 | 7.02 |
| 581.05 | 6.50 | 6.50 |
| 529.60 | 5.11 | 5.11 |
| 558.64 | 5.72 | 5.72 |
| 585.67 | 5.07 | 5.07 |
| 553.63 | 5.58 | 5.58 |
| 553.63 | 5.58 | 5.58 |
| 484.99 | 6.36 | 6.36 |
| 520.97 | 7.13 | 7.13 |
| 500.00 | 5.30 | 5.30 |