Inhibition of CYP3A4/CYP3A5-mediated testosterone 6beta-hydroxylation in human liver microsomes

Basic Information

ID: ALA2043697

Type: ADME

Description: Inhibition of CYP3A4/CYP3A5-mediated testosterone 6beta-hydroxylation in human liver microsomes

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  Cytochrome P450 3A4/3A5(ALA2111472)

Document:  ALA2040800

Inhibition of CYP3A4/CYP3A5-mediated testosterone 6beta-hydroxylation in human liver microsomes: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
355.422.802.80
393.393.823.82