Basic Information
ID: ALA2044568
Type: Functional
Description: Positive allosteric modulation of human muscarinic M1 receptor expressed in CHO-NFAT cells assessed as potentiation of acetylcholine-induced calcium flux after 1 hr by FLIPR assay
Organism: Homo sapiens
Cell type: CHO-NFAT
Activity Charts
Bioactivity
Activity Types for Assay ALA2044568
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.43 | 2.19 | 2.19 |
| 362.43 | 3.38 | 3.38 |
| 295.29 | 2.08 | 2.08 |
| 293.28 | 2.23 | 2.23 |
| 279.30 | 2.59 | 2.59 |
| 313.74 | 3.24 | 3.24 |
| 355.39 | 4.26 | 4.26 |
| 356.38 | 3.65 | 3.65 |
| 356.38 | 3.65 | 3.65 |
| 286.33 | 1.98 | 1.98 |
| 348.40 | 2.99 | 2.99 |
| 363.42 | 2.32 | 2.32 |
| 377.40 | 1.85 | 1.85 |
| 364.41 | 1.71 | 1.71 |
| 442.31 | 3.08 | 3.08 |
| 431.41 | 3.34 | 3.34 |