Basic Information
ID: ALA2045142
Type: Binding
Description: Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hrs by Gli-luciferase reporter assay
Organism: Mus musculus
Cell type: C3H 10T1/2
Activity Charts
Bioactivity
Activity Types for Assay ALA2045142
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.31 | 4.71 | 4.71 |
| 349.44 | 3.52 | 3.52 |
| 371.40 | 4.25 | 4.25 |
| 377.44 | 3.79 | 3.79 |
| 392.46 | 2.90 | 2.90 |
| 407.47 | 3.29 | 3.29 |
| 379.46 | 3.53 | 3.53 |
| 417.44 | 4.54 | 4.54 |
| 383.88 | 4.17 | 4.17 |
| 374.45 | 3.39 | 3.39 |
| 374.45 | 3.39 | 3.39 |
| 350.43 | 2.91 | 2.91 |