Basic Information
ID: ALA2045263
Type: Binding
Description: Inhibition of Plasmodium falciparum falcipain 2 using substrate benzoxycarbonyl-Leu-Arg-7-amino-4-methyl-coumarin preincubated for 30 mins before substrate addition by fluorescence assay
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA2045263
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 357.41 | -1.46 | -1.46 |
| 282.34 | 2.39 | 2.39 |
| 583.13 | 6.19 | 6.19 |
| 583.13 | 6.19 | 6.19 |
| 597.16 | 6.50 | 6.50 |
| 625.21 | 7.31 | 7.31 |
| 613.16 | 6.20 | 6.20 |
| 598.15 | 5.77 | 5.77 |
| 601.12 | 6.33 | 6.33 |
| 601.12 | 6.33 | 6.33 |
| 617.58 | 6.84 | 6.84 |
| 662.03 | 6.95 | 6.95 |
| 628.13 | 6.10 | 6.10 |
| 628.13 | 6.10 | 6.10 |
| 628.13 | 6.10 | 6.10 |
| 308.77 | 4.54 | 4.54 |
| 322.80 | 4.85 | 4.85 |
| 350.85 | 5.66 | 5.66 |
| 338.79 | 4.55 | 4.55 |
| 326.76 | 4.68 | 4.68 |
| 326.76 | 4.68 | 4.68 |
| 343.21 | 5.19 | 5.19 |
| 387.66 | 5.30 | 5.30 |
| 353.77 | 4.45 | 4.45 |
| 353.77 | 4.45 | 4.45 |
| 353.77 | 4.45 | 4.45 |