Basic Information
ID: ALA2045705
Type: Binding
Description: Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell assessed as inhibition of PGE2 production preincubated for 15 mins before substrate addition by RP-HPLC method
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA2045705
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.39 | 4.27 | 4.27 |
| 529.55 | 4.11 | 4.11 |
| 513.51 | 3.74 | 3.74 |
| 415.41 | 3.85 | 3.85 |
| 648.70 | 6.29 | 6.29 |
| 444.40 | 3.97 | 3.97 |
| 444.40 | 3.97 | 3.97 |
| 416.39 | 3.97 | 3.97 |
| 490.47 | 4.29 | 4.29 |
| 608.96 | 7.52 | 7.52 |
| 406.42 | 4.33 | 4.33 |
| 416.39 | 3.97 | 3.97 |
| 444.40 | 3.97 | 3.97 |
| 578.98 | 7.19 | 7.19 |
| 563.96 | 7.61 | 7.61 |
| 614.00 | 6.80 | 6.80 |