ID: ALA2046256
Type: Binding
Description: Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assay
Bioactivity
Activity Types for Assay ALA2046256
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
281.23 | 4.15 | 4.15 |
213.24 | 3.13 | 3.13 |
247.68 | 3.78 | 3.78 |
227.26 | 3.44 | 3.44 |
257.25 | 2.83 | 2.83 |
243.26 | 3.14 | 3.14 |
258.23 | 3.04 | 3.04 |
243.26 | 3.14 | 3.14 |
213.24 | 3.13 | 3.13 |
213.24 | 3.13 | 3.13 |
258.23 | 3.04 | 3.04 |
255.27 | 3.33 | 3.33 |
281.23 | 4.15 | 4.15 |
247.68 | 3.78 | 3.78 |
292.13 | 3.89 | 3.89 |
269.34 | 4.43 | 4.43 |
243.26 | 3.14 | 3.14 |
227.26 | 3.44 | 3.44 |
299.37 | 4.43 | 4.43 |
287.27 | 2.84 | 2.84 |
303.31 | 3.15 | 3.15 |
271.32 | 3.75 | 3.75 |
323.27 | 4.35 | 4.35 |
255.27 | 3.33 | 3.33 |
300.27 | 3.24 | 3.24 |
297.31 | 3.53 | 3.53 |
323.27 | 4.35 | 4.35 |
285.30 | 3.34 | 3.34 |
300.27 | 3.24 | 3.24 |
297.31 | 3.53 | 3.53 |
289.72 | 3.98 | 3.98 |
285.30 | 3.34 | 3.34 |
269.30 | 3.64 | 3.64 |
300.27 | 3.24 | 3.24 |
297.31 | 3.53 | 3.53 |
323.27 | 4.35 | 4.35 |
289.72 | 3.98 | 3.98 |
334.17 | 4.09 | 4.09 |
285.30 | 3.34 | 3.34 |
269.30 | 3.64 | 3.64 |
311.38 | 4.63 | 4.63 |
299.28 | 3.03 | 3.03 |
330.30 | 3.25 | 3.25 |
391.27 | 5.37 | 5.37 |
315.33 | 3.35 | 3.35 |
283.33 | 3.95 | 3.95 |
343.29 | 2.73 | 2.73 |
281.23 | 4.15 | 4.15 |
258.23 | 3.04 | 3.04 |
255.27 | 3.33 | 3.33 |
281.23 | 4.15 | 4.15 |
243.26 | 3.14 | 3.14 |
258.23 | 3.04 | 3.04 |
255.27 | 3.33 | 3.33 |
247.68 | 3.78 | 3.78 |
243.26 | 3.14 | 3.14 |
227.26 | 3.44 | 3.44 |
257.25 | 2.83 | 2.83 |
257.25 | 2.83 | 2.83 |
241.29 | 3.75 | 3.75 |
299.28 | 3.03 | 3.03 |
326.23 | 4.06 | 4.06 |
288.26 | 3.05 | 3.05 |
342.23 | 3.94 | 3.94 |
349.23 | 5.17 | 5.17 |
273.29 | 3.15 | 3.15 |
241.29 | 3.75 | 3.75 |
301.25 | 2.52 | 2.52 |
281.23 | 4.15 | 4.15 |
243.26 | 3.14 | 3.14 |
258.23 | 3.04 | 3.04 |
247.68 | 3.78 | 3.78 |
243.26 | 3.14 | 3.14 |
227.26 | 3.44 | 3.44 |
258.23 | 3.04 | 3.04 |
255.27 | 3.33 | 3.33 |
247.68 | 3.78 | 3.78 |
292.13 | 3.89 | 3.89 |
243.26 | 3.14 | 3.14 |
227.26 | 3.44 | 3.44 |
269.34 | 4.43 | 4.43 |
257.25 | 2.83 | 2.83 |
288.26 | 3.05 | 3.05 |
241.29 | 3.75 | 3.75 |
273.29 | 3.15 | 3.15 |
243.26 | 3.14 | 3.14 |
258.23 | 3.04 | 3.04 |
255.27 | 3.33 | 3.33 |
255.27 | 3.33 | 3.33 |
247.68 | 3.78 | 3.78 |
227.26 | 3.44 | 3.44 |
269.34 | 4.43 | 4.43 |
257.25 | 2.83 | 2.83 |
288.26 | 3.05 | 3.05 |
273.29 | 3.15 | 3.15 |
241.29 | 3.75 | 3.75 |
311.26 | 4.16 | 4.16 |
243.26 | 3.14 | 3.14 |
273.29 | 3.15 | 3.15 |
288.26 | 3.05 | 3.05 |
277.71 | 3.79 | 3.79 |
273.29 | 3.15 | 3.15 |
257.29 | 3.45 | 3.45 |
287.27 | 2.84 | 2.84 |
288.26 | 3.05 | 3.05 |
285.30 | 3.34 | 3.34 |
277.71 | 3.79 | 3.79 |
322.16 | 3.90 | 3.90 |
273.29 | 3.15 | 3.15 |
257.29 | 3.45 | 3.45 |