Basic Information
ID: ALA2049552
Type: Functional
Description: Antitumor activity against human COLO205 cells expressing B-raf V600E mutant xenografted in po dosed NCr nude mouse assessed as decrease in tumor volume administered once daily for 21 days measured twice a week up to 21 days
Organism: Homo sapiens
Cell type: COLO 205
Activity Charts
Bioactivity
Activity Types for Assay ALA2049552
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.42 | 2.65 | 2.65 |
| 461.90 | 3.42 | 3.42 |