Basic Information
ID: ALA2049638
Type: Binding
Description: Inhibition of human recombinant N-terminal-His6 tagged FPPS expressed in Escherichia coli BL21 using [14C]IPP and GPP as substrate incubated for 10 mins prior to substrate addition measured after 10 mins by scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2049638
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.11 | -0.37 | -0.37 |
| 268.10 | 0.13 | 0.13 |
| 343.21 | 2.40 | 2.40 |
| 448.48 | 6.20 | 6.20 |
| 401.23 | 2.15 | 2.15 |
| 361.20 | 2.27 | 2.27 |
| 343.21 | 1.97 | 1.97 |
| 344.20 | 1.80 | 1.80 |
| 344.20 | 1.80 | 1.80 |
| 384.23 | 1.68 | 1.68 |
| 402.28 | 2.59 | 2.59 |
| 414.29 | 2.73 | 2.73 |
| 358.23 | 2.11 | 2.11 |
| 428.32 | 3.12 | 3.12 |