Basic Information
ID: ALA2049639
Type: Binding
Description: Inhibition of human recombinant N-terminal-His6 tagged FPPS expressed in Escherichia coli BL21 using [3H]IPP and GPP as substrate at 1 uM incubated for 10 mins prior to substrate addition measured after 20 mins by liquid scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2049639
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.11 | -0.37 | -0.37 |
| 268.10 | 0.13 | 0.13 |
| 343.21 | 2.40 | 2.40 |
| 401.23 | 2.15 | 2.15 |
| 344.20 | 1.80 | 1.80 |
| 361.20 | 2.27 | 2.27 |
| 343.21 | 1.97 | 1.97 |
| 344.20 | 1.80 | 1.80 |
| 344.20 | 1.80 | 1.80 |
| 384.23 | 1.68 | 1.68 |
| 402.28 | 2.59 | 2.59 |
| 414.29 | 2.73 | 2.73 |
| 358.23 | 2.11 | 2.11 |
| 428.32 | 3.12 | 3.12 |
| 374.23 | 1.81 | 1.81 |
| 374.23 | 1.81 | 1.81 |
| 374.23 | 1.81 | 1.81 |
| 290.11 | -1.12 | -1.12 |