Basic Information
ID: ALA2050420
Type: Binding
Description: Inhibition of human recombinant HDAC1 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2050420
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 664.40 | 3.68 | 3.68 |
| 347.23 | 2.01 | 2.01 |
| 361.26 | 2.31 | 2.31 |
| 692.45 | 4.29 | 4.29 |
| 333.21 | 1.57 | 1.57 |
| 347.23 | 1.88 | 1.88 |
| 361.26 | 2.18 | 2.18 |
| 375.29 | 2.48 | 2.48 |
| 692.45 | 4.03 | 4.03 |
| 720.51 | 4.63 | 4.63 |
| 347.23 | 1.75 | 1.75 |
| 361.26 | 2.05 | 2.05 |
| 332.22 | 1.75 | 1.75 |
| 346.25 | 2.05 | 2.05 |
| 634.37 | 3.16 | 3.16 |
| 662.42 | 3.77 | 3.77 |
| 318.19 | 1.31 | 1.31 |
| 332.22 | 1.62 | 1.62 |
| 346.25 | 1.49 | 1.49 |
| 360.28 | 1.79 | 1.79 |
| 662.43 | 2.65 | 2.65 |
| 690.48 | 3.26 | 3.26 |
| 332.22 | 1.06 | 1.06 |
| 346.25 | 1.36 | 1.36 |
| 630.42 | 5.13 | 5.13 |
| 316.22 | 2.30 | 2.30 |
| 360.16 | 0.54 | 0.54 |
| 374.19 | 0.93 | 0.93 |
| 286.65 | 0.89 | 0.89 |
| 238.31 | 1.11 | 1.11 |
| 254.31 | 0.81 | 0.81 |
| 256.30 | 1.24 | 1.24 |
| 284.41 | 1.83 | 1.83 |
| 394.23 | 1.72 | 1.72 |
| 335.20 | 2.01 | 2.01 |
| 363.30 | 2.59 | 2.59 |
| 424.26 | 1.73 | 1.73 |
| 377.26 | 1.89 | 1.89 |
| 298.36 | 1.12 | 1.12 |
| 283.31 | 1.01 | 1.01 |
| 362.20 | 1.78 | 1.78 |
| 412.10 | 2.34 | 2.34 |
| 314.43 | 1.84 | 1.84 |
| 281.38 | 1.17 | 1.17 |
| 360.28 | 1.93 | 1.93 |