Basic Information
ID: ALA2050456
Type: Binding
Description: Inhibition of B-raf V600E mutant-mediated Erk phosphorylation in human MALM-3M cells by fluorometric analysis
Organism: Homo sapiens
Cell type: MALM-3M
Activity Charts
Bioactivity
Activity Types for Assay ALA2050456
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.42 | 2.65 | 2.65 |
| 370.38 | 2.35 | 2.35 |
| 386.38 | 2.13 | 2.13 |
| 400.41 | 2.59 | 2.59 |
| 430.44 | 1.95 | 1.95 |
| 400.41 | 2.16 | 2.16 |
| 411.39 | 2.43 | 2.43 |
| 441.42 | 2.44 | 2.44 |
| 421.43 | 2.89 | 2.89 |
| 437.88 | 3.41 | 3.41 |
| 437.88 | 3.41 | 3.41 |
| 455.87 | 3.36 | 3.36 |
| 427.46 | 2.96 | 2.96 |
| 443.91 | 3.47 | 3.47 |
| 443.91 | 3.47 | 3.47 |
| 461.90 | 3.42 | 3.42 |