Basic Information
ID: ALA2050727
Type: Functional
Description: Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction by liquid scintillation counting
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2050727
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.65 | 3.27 | 3.27 |
| 250.66 | 3.13 | 3.13 |
| 267.12 | 3.64 | 3.64 |
| 232.67 | 2.99 | 2.99 |
| 250.66 | 3.13 | 3.13 |
| 250.66 | 3.13 | 3.13 |
| 300.67 | 4.01 | 4.01 |
| 300.67 | 4.01 | 4.01 |
| 308.77 | 4.65 | 4.65 |
| 262.70 | 3.00 | 3.00 |
| 260.72 | 3.60 | 3.60 |
| 301.56 | 4.29 | 4.29 |
| 267.12 | 3.64 | 3.64 |
| 285.11 | 3.78 | 3.78 |
| 318.66 | 4.15 | 4.15 |
| 311.75 | 1.63 | 1.63 |
| 318.66 | 4.15 | 4.15 |
| 285.11 | 3.78 | 3.78 |
| 264.69 | 3.43 | 3.43 |
| 257.68 | 2.86 | 2.86 |
| 268.65 | 3.27 | 3.27 |
| 324.77 | 4.78 | 4.78 |
| 275.67 | 3.00 | 3.00 |
| 280.69 | 3.14 | 3.14 |
| 294.71 | 3.53 | 3.53 |
| 308.74 | 3.91 | 3.91 |
| 342.76 | 4.92 | 4.92 |
| 376.82 | 5.42 | 5.42 |
| 408.81 | 4.10 | 4.10 |
| 390.84 | 5.56 | 5.56 |
| 422.84 | 4.24 | 4.24 |
| 324.81 | 4.63 | 4.63 |
| 338.84 | 4.87 | 4.87 |
| 370.83 | 3.56 | 3.56 |
| 369.83 | 4.78 | 4.78 |
| 251.65 | 2.52 | 2.52 |
| 269.64 | 2.66 | 2.66 |
| 268.10 | 3.04 | 3.04 |
| 301.65 | 3.40 | 3.40 |
| 286.09 | 3.17 | 3.17 |
| 265.68 | 2.83 | 2.83 |