Basic Information
ID: ALA2050876
Type: Binding
Description: Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 2 uM after 48 hrs by flow cytometric analysis
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2050876
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.31 | 3.60 | 3.60 |
| 284.31 | 3.31 | 3.31 |
| 328.36 | 3.62 | 3.62 |
| 356.42 | 4.40 | 4.40 |
| 386.44 | 4.41 | 4.41 |
| 268.31 | 3.60 | 3.60 |
| 314.34 | 3.31 | 3.31 |
| 358.39 | 3.63 | 3.63 |
| 358.39 | 3.63 | 3.63 |
| 358.39 | 3.63 | 3.63 |
| 314.34 | 3.31 | 3.31 |
| 358.39 | 3.63 | 3.63 |
| 344.36 | 3.32 | 3.32 |
| 298.34 | 3.61 | 3.61 |
| 298.34 | 3.61 | 3.61 |
| 344.36 | 3.32 | 3.32 |
| 328.36 | 3.62 | 3.62 |
| 358.39 | 3.63 | 3.63 |
| 358.39 | 3.63 | 3.63 |
| 388.42 | 3.63 | 3.63 |
| 344.36 | 3.32 | 3.32 |
| 344.36 | 3.32 | 3.32 |
| 344.36 | 3.32 | 3.32 |
| 314.34 | 3.31 | 3.31 |
| 314.34 | 3.31 | 3.31 |
| 314.34 | 3.31 | 3.31 |
| 314.34 | 3.31 | 3.31 |
| 314.34 | 3.31 | 3.31 |
| 314.34 | 3.31 | 3.31 |
| 472.58 | 5.97 | 5.97 |
| 374.39 | 3.33 | 3.33 |
| 291.35 | 4.08 | 4.08 |
| 321.38 | 4.09 | 4.09 |
| 321.38 | 4.09 | 4.09 |
| 351.40 | 4.10 | 4.10 |
| 351.40 | 4.10 | 4.10 |
| 381.43 | 4.11 | 4.11 |
| 314.39 | 4.57 | 4.57 |
| 356.42 | 4.40 | 4.40 |
| 374.39 | 3.33 | 3.33 |
| 374.39 | 3.33 | 3.33 |
| 321.38 | 4.09 | 4.09 |
| 351.40 | 4.10 | 4.10 |
| 321.38 | 4.09 | 4.09 |