Basic Information
ID: ALA2050885
Type: Binding
Description: Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA2050885
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.47 | 7.62 | 7.62 |
| 514.05 | 7.03 | 7.03 |
| 542.47 | 7.62 | 7.62 |
| 538.05 | 6.98 | 6.98 |
| 538.05 | 6.98 | 6.98 |
| 508.02 | 6.97 | 6.97 |
| 466.37 | 5.96 | 5.96 |
| 514.41 | 6.98 | 6.98 |
| 466.37 | 5.96 | 5.96 |
| 484.36 | 6.10 | 6.10 |
| 500.81 | 6.61 | 6.61 |
| 445.95 | 5.61 | 5.61 |
| 514.41 | 6.59 | 6.59 |
| 467.57 | 5.42 | 5.42 |
| 396.45 | 3.97 | 3.97 |
| 481.38 | 6.35 | 6.35 |
| 452.56 | 4.91 | 4.91 |
| 313.74 | 2.69 | 2.69 |
| 259.69 | 3.16 | 3.16 |
| 536.08 | 7.29 | 7.29 |
| 508.02 | 6.97 | 6.97 |
| 526.01 | 7.11 | 7.11 |
| 445.95 | 5.68 | 5.68 |
| 488.03 | 6.70 | 6.70 |
| 542.47 | 7.62 | 7.62 |