ID: ALA2050886
Type: Binding
Description: Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: HeLa
Bioactivity
Activity Types for Assay ALA2050886
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
542.47 | 7.62 | 7.62 |
538.05 | 6.98 | 6.98 |
508.02 | 6.97 | 6.97 |
466.37 | 5.96 | 5.96 |
466.37 | 5.96 | 5.96 |
484.36 | 6.10 | 6.10 |
445.95 | 5.61 | 5.61 |
514.41 | 6.59 | 6.59 |
542.47 | 7.62 | 7.62 |