Assay Report Card

Basic Information

ID: ALA2050887

Type: Binding

Description: Inhibition of mPGES-1 derived from LPS stimulated mouse RAW264.7 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control

Organism: Mus musculus

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
542.477.627.62
538.056.986.98
508.026.976.97
466.375.965.96
466.375.965.96
484.366.106.10
445.955.615.61
514.416.596.59
542.477.627.62