Basic Information
ID: ALA2050887
Type: Binding
Description: Inhibition of mPGES-1 derived from LPS stimulated mouse RAW264.7 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA2050887
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.47 | 7.62 | 7.62 |
| 538.05 | 6.98 | 6.98 |
| 508.02 | 6.97 | 6.97 |
| 466.37 | 5.96 | 5.96 |
| 466.37 | 5.96 | 5.96 |
| 484.36 | 6.10 | 6.10 |
| 445.95 | 5.61 | 5.61 |
| 514.41 | 6.59 | 6.59 |
| 542.47 | 7.62 | 7.62 |