Basic Information
ID: ALA2050992
Type: Binding
Description: Inhibition of 5-lipoxygenase/FLAP in calcium ionophore-stimulated human whole blood assessed as residual 12(s)HETE level at 10 uM preincubated for 15 mins prior to calcium ionophore-stimulation measured after 15 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA2050992
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.47 | 7.62 | 7.62 |
| 538.05 | 6.98 | 6.98 |
| 508.02 | 6.97 | 6.97 |
| 466.37 | 5.96 | 5.96 |
| 466.37 | 5.96 | 5.96 |
| 484.36 | 6.10 | 6.10 |
| 445.95 | 5.61 | 5.61 |
| 542.47 | 7.62 | 7.62 |