Basic Information
ID: ALA2051080
Type: ADME
Description: Inhibition of CYP3A4 using BFC substrate in which compound added to reaction mixture before addition of BFC substrate by fluorometric assay
Activity Charts
Bioactivity
Activity Types for Assay ALA2051080
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 408.88 | 1.84 | 1.84 |
| 376.41 | 0.46 | 0.46 |
| 448.47 | 1.65 | 1.65 |
| 444.52 | 2.97 | 2.97 |
| 358.43 | 1.46 | 1.46 |
| 356.46 | 2.02 | 2.02 |
| 368.47 | 2.33 | 2.33 |
| 386.49 | 2.03 | 2.03 |
| 402.49 | 1.13 | 1.13 |
| 386.49 | 2.03 | 2.03 |
| 402.49 | 1.13 | 1.13 |
| 400.52 | 2.42 | 2.42 |
| 416.51 | 1.52 | 1.52 |
| 370.49 | 2.33 | 2.33 |
| 386.49 | 1.43 | 1.43 |
| 416.51 | 2.04 | 2.04 |
| 432.51 | 1.14 | 1.14 |