Basic Information
ID: ALA2051190
Type: ADME
Description: Potency index, ratio of IC50 for CYP3A4 (unknown origin) using BFC substrate in which compound added to reaction mixture simultaneously with BFC substrate to IC50 for CYP3A4 using BFC substrate in which compound added to reaction mixture before addition of BFC substrate
Activity Charts
Bioactivity
Activity Types for Assay ALA2051190
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 408.88 | 1.84 | 1.84 |
| 376.41 | 0.46 | 0.46 |
| 448.47 | 1.65 | 1.65 |
| 444.52 | 2.97 | 2.97 |
| 358.43 | 1.46 | 1.46 |
| 356.46 | 2.02 | 2.02 |
| 368.47 | 2.33 | 2.33 |
| 386.49 | 2.03 | 2.03 |
| 402.49 | 1.13 | 1.13 |
| 386.49 | 2.03 | 2.03 |
| 402.49 | 1.13 | 1.13 |
| 400.52 | 2.42 | 2.42 |
| 416.51 | 1.52 | 1.52 |
| 370.49 | 2.33 | 2.33 |
| 386.49 | 1.43 | 1.43 |
| 416.51 | 2.04 | 2.04 |
| 432.51 | 1.14 | 1.14 |