Basic Information
ID: ALA2060741
Type: Functional
Description: Agonist activity at Rev-Erbalpha expressed in HEK293 cells coexpressing BamII promoter assessed as repression of transcription after 24 hrs by dual-Glo luciferase assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2060741
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.90 | 4.65 | 4.65 |
| 437.95 | 4.79 | 4.79 |
| 255.74 | 2.77 | 2.77 |
| 346.86 | 4.08 | 4.08 |
| 337.89 | 4.67 | 4.67 |
| 402.95 | 5.29 | 5.29 |
| 351.90 | 4.75 | 4.75 |
| 335.83 | 3.41 | 3.41 |
| 407.45 | 3.91 | 3.91 |
| 362.45 | 4.00 | 4.00 |
| 392.48 | 4.01 | 4.01 |
| 380.44 | 4.14 | 4.14 |
| 412.51 | 5.15 | 5.15 |
| 412.51 | 5.15 | 5.15 |
| 426.52 | 3.50 | 3.50 |
| 426.49 | 4.79 | 4.79 |
| 462.55 | 4.34 | 4.34 |
| 354.82 | 3.48 | 3.48 |
| 340.79 | 3.40 | 3.40 |
| 339.80 | 2.80 | 2.80 |
| 321.79 | 3.84 | 3.84 |
| 422.94 | 6.67 | 6.67 |
| 440.87 | 6.53 | 6.53 |
| 429.95 | 6.12 | 6.12 |
| 439.95 | 4.12 | 4.12 |
| 430.91 | 5.15 | 5.15 |
| 378.93 | 5.89 | 5.89 |
| 466.00 | 5.57 | 5.57 |
| 436.92 | 6.31 | 6.31 |
| 436.94 | 5.01 | 5.01 |
| 480.03 | 5.96 | 5.96 |
| 480.03 | 5.96 | 5.96 |
| 466.00 | 5.71 | 5.71 |
| 466.00 | 5.71 | 5.71 |
| 451.98 | 5.32 | 5.32 |
| 379.91 | 4.26 | 4.26 |
| 456.01 | 5.83 | 5.83 |
| 407.92 | 4.18 | 4.18 |
| 485.99 | 5.83 | 5.83 |
| 449.96 | 4.96 | 4.96 |
| 485.01 | 5.87 | 5.87 |
| 465.02 | 5.14 | 5.14 |
| 530.01 | 5.77 | 5.77 |
| 443.98 | 3.59 | 3.59 |
| 520.08 | 5.33 | 5.33 |
| 520.08 | 5.16 | 5.16 |
| 556.11 | 6.18 | 6.18 |