Assay Report Card

Basic Information

ID: ALA2061060

Type: Binding

Description: Inhibition of APE1 in human HeLa whole cell extract using [35P]-5'-AP-DNA as substrate assessed as activity remaining at 100 uM incubated for 15 mins prior to substrate addition measured after 5 mins by PAGE analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
371.534.754.75
357.504.714.71
397.575.265.26
385.565.145.14
315.423.593.59
385.564.794.79
355.464.284.28
343.483.973.97
365.433.873.87
329.453.633.63