Basic Information
ID: ALA2061115
Type: Binding
Description: Competitive inhibition of recombinant APE1 using [35P]-5'-AP-DNA as substrate assessed as decrease in APE1-DNA complex formation at 10 to 100 uM preincubated with substrate for 15 mins prior to enzyme addition measured after 5 mins by electrophoretic mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2061115
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.53 | 4.75 | 4.75 |
| 315.42 | 3.59 | 3.59 |