Basic Information
ID: ALA2061325
Type: Functional
Description: Inhibition of cholesterol synthesis in rat hepatocytes assessed as formation of cholesterol using [14C]mevalonolactone as substrate after 1 hr by radioactivity assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Hepatocyte
Target: Hepatocyte(ALA613362)
Document: ALA2057169
Inhibition of cholesterol synthesis in rat hepatocytes assessed as formation of cholesterol using [14C]mevalonolactone as substrate after 1 hr by radioactivity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2061325
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.88 | 4.87 | 4.87 |
| 413.86 | 4.78 | 4.78 |
| 539.03 | 5.41 | 5.41 |
| 448.30 | 5.44 | 5.44 |
| 470.95 | 4.84 | 4.84 |
| 512.99 | 4.62 | 4.62 |
| 539.03 | 5.41 | 5.41 |
| 539.03 | 5.41 | 5.41 |
| 525.00 | 5.02 | 5.02 |
| 525.00 | 5.02 | 5.02 |
| 540.02 | 3.93 | 3.93 |
| 470.91 | 3.90 | 3.90 |
| 484.94 | 4.29 | 4.29 |
| 532.98 | 6.04 | 6.04 |
| 427.88 | 5.17 | 5.17 |
| 553.06 | 5.80 | 5.80 |
| 539.03 | 5.41 | 5.41 |
| 510.97 | 4.63 | 4.63 |
| 525.00 | 5.02 | 5.02 |
| 569.05 | 5.18 | 5.18 |
| 583.08 | 5.57 | 5.57 |
| 583.08 | 5.43 | 5.43 |
| 541.00 | 4.40 | 4.40 |
| 568.03 | 3.84 | 3.84 |
| 494.94 | 4.69 | 4.69 |
| 508.96 | 4.62 | 4.62 |
| 508.96 | 4.62 | 4.62 |
| 538.99 | 4.59 | 4.59 |
| 567.04 | 5.37 | 5.37 |
| 595.10 | 6.15 | 6.15 |
| 507.97 | 5.22 | 5.22 |
| 507.97 | 5.22 | 5.22 |
| 493.95 | 5.29 | 5.29 |
| 507.97 | 5.22 | 5.22 |
| 495.92 | 4.08 | 4.08 |
| 509.95 | 4.01 | 4.01 |
| 509.95 | 4.01 | 4.01 |
| 523.98 | 4.40 | 4.40 |
| 538.00 | 4.75 | 4.75 |
| 535.99 | 4.50 | 4.50 |
| 568.03 | 4.77 | 4.77 |