Basic Information
ID: ALA2061431
Type: Binding
Description: Inhibition of human recombinant Top1-mediated DNA cleavage by polyacrylamide gel electrophoresis relative to camptothecin
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2061431
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.81 | 2.56 | 2.56 |
| 354.84 | 2.95 | 2.95 |
| 326.78 | 2.17 | 2.17 |
| 368.86 | 3.34 | 3.34 |
| 382.89 | 3.73 | 3.73 |
| 396.92 | 4.12 | 4.12 |
| 410.95 | 4.51 | 4.51 |
| 424.97 | 4.90 | 4.90 |
| 439.00 | 5.29 | 5.29 |
| 453.03 | 5.68 | 5.68 |
| 467.05 | 6.07 | 6.07 |
| 504.56 | 3.60 | 3.60 |
| 762.78 | 5.79 | 5.79 |
| 368.41 | 1.76 | 1.76 |
| 382.44 | 2.15 | 2.15 |
| 396.47 | 2.54 | 2.54 |
| 410.50 | 2.93 | 2.93 |
| 424.52 | 3.32 | 3.32 |
| 438.55 | 3.71 | 3.71 |
| 452.58 | 4.10 | 4.10 |
| 466.60 | 4.49 | 4.49 |
| 480.63 | 4.88 | 4.88 |
| 494.66 | 5.27 | 5.27 |
| 508.68 | 5.66 | 5.66 |
| 430.49 | 3.19 | 3.19 |
| 444.51 | 3.58 | 3.58 |
| 458.54 | 3.97 | 3.97 |
| 472.57 | 4.36 | 4.36 |
| 486.59 | 4.75 | 4.75 |
| 500.62 | 5.14 | 5.14 |
| 514.65 | 5.53 | 5.53 |
| 528.67 | 5.92 | 5.92 |
| 542.70 | 6.31 | 6.31 |
| 556.73 | 6.70 | 6.70 |
| 570.76 | 7.09 | 7.09 |
| 444.51 | 3.50 | 3.50 |
| 458.54 | 3.89 | 3.89 |
| 472.57 | 4.28 | 4.28 |
| 486.59 | 4.67 | 4.67 |
| 500.62 | 5.06 | 5.06 |
| 514.65 | 5.45 | 5.45 |
| 528.67 | 5.84 | 5.84 |
| 542.70 | 6.23 | 6.23 |
| 556.73 | 6.62 | 6.62 |
| 570.76 | 7.01 | 7.01 |
| 584.78 | 7.40 | 7.40 |
| 509.38 | 3.95 | 3.95 |
| 523.41 | 4.34 | 4.34 |
| 537.44 | 4.73 | 4.73 |
| 551.46 | 5.12 | 5.12 |
| 565.49 | 5.51 | 5.51 |
| 579.52 | 5.90 | 5.90 |
| 593.54 | 6.29 | 6.29 |
| 607.57 | 6.68 | 6.68 |
| 621.60 | 7.07 | 7.07 |
| 635.62 | 7.46 | 7.46 |
| 649.65 | 7.85 | 7.85 |
| 565.61 | 5.16 | 5.16 |
| 488.52 | 3.31 | 3.31 |
| 562.60 | 3.39 | 3.39 |
| 489.51 | 3.49 | 3.49 |