ID: ALA2061432
Type: Binding
Description: Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed as prevention of generation of oligonucleotide with free 3'-phosphate after 15 mins by PAGE analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2061432
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
340.81 | 2.56 | 2.56 |
305.33 | 2.60 | 2.60 |
291.31 | 2.21 | 2.21 |
333.39 | 3.38 | 3.38 |
319.36 | 2.99 | 2.99 |
354.84 | 2.95 | 2.95 |
326.78 | 2.17 | 2.17 |
549.53 | 5.87 | 5.87 |
368.86 | 3.34 | 3.34 |
382.89 | 3.73 | 3.73 |
396.92 | 4.12 | 4.12 |
410.95 | 4.51 | 4.51 |
424.97 | 4.90 | 4.90 |
439.00 | 5.29 | 5.29 |
453.03 | 5.68 | 5.68 |
467.05 | 6.07 | 6.07 |
504.56 | 3.60 | 3.60 |
632.76 | 8.56 | 8.56 |
646.79 | 8.95 | 8.95 |
660.81 | 9.34 | 9.34 |
762.78 | 5.79 | 5.79 |
347.41 | 3.77 | 3.77 |
361.44 | 4.16 | 4.16 |
459.52 | 4.32 | 4.32 |
473.55 | 4.71 | 4.71 |
487.58 | 5.10 | 5.10 |
501.60 | 5.49 | 5.49 |
515.63 | 5.88 | 5.88 |
368.41 | 1.76 | 1.76 |
382.44 | 2.15 | 2.15 |
396.47 | 2.54 | 2.54 |
410.50 | 2.93 | 2.93 |
424.52 | 3.32 | 3.32 |
438.55 | 3.71 | 3.71 |
452.58 | 4.10 | 4.10 |
466.60 | 4.49 | 4.49 |
480.63 | 4.88 | 4.88 |
494.66 | 5.27 | 5.27 |
508.68 | 5.66 | 5.66 |
430.49 | 3.19 | 3.19 |
444.51 | 3.58 | 3.58 |
458.54 | 3.97 | 3.97 |
472.57 | 4.36 | 4.36 |
486.59 | 4.75 | 4.75 |
500.62 | 5.14 | 5.14 |
514.65 | 5.53 | 5.53 |
528.67 | 5.92 | 5.92 |
542.70 | 6.31 | 6.31 |
556.73 | 6.70 | 6.70 |
570.76 | 7.09 | 7.09 |
444.51 | 3.50 | 3.50 |
458.54 | 3.89 | 3.89 |
472.57 | 4.28 | 4.28 |
486.59 | 4.67 | 4.67 |
500.62 | 5.06 | 5.06 |
514.65 | 5.45 | 5.45 |
528.67 | 5.84 | 5.84 |
542.70 | 6.23 | 6.23 |
556.73 | 6.62 | 6.62 |
570.76 | 7.01 | 7.01 |
584.78 | 7.40 | 7.40 |
509.38 | 3.95 | 3.95 |
523.41 | 4.34 | 4.34 |
537.44 | 4.73 | 4.73 |
551.46 | 5.12 | 5.12 |
565.49 | 5.51 | 5.51 |
579.52 | 5.90 | 5.90 |
593.54 | 6.29 | 6.29 |
607.57 | 6.68 | 6.68 |
621.60 | 7.07 | 7.07 |
635.62 | 7.46 | 7.46 |
649.65 | 7.85 | 7.85 |
565.61 | 5.16 | 5.16 |
488.52 | 3.31 | 3.31 |
562.60 | 3.39 | 3.39 |
489.51 | 3.49 | 3.49 |