Assay Report Card

Basic Information

ID: ALA2061432

Type: Binding

Description: Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed as prevention of generation of oligonucleotide with free 3'-phosphate after 15 mins by PAGE analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
340.812.562.56
305.332.602.60
291.312.212.21
333.393.383.38
319.362.992.99
354.842.952.95
326.782.172.17
549.535.875.87
368.863.343.34
382.893.733.73
396.924.124.12
410.954.514.51
424.974.904.90
439.005.295.29
453.035.685.68
467.056.076.07
504.563.603.60
632.768.568.56
646.798.958.95
660.819.349.34
762.785.795.79
347.413.773.77
361.444.164.16
459.524.324.32
473.554.714.71
487.585.105.10
501.605.495.49
515.635.885.88
368.411.761.76
382.442.152.15
396.472.542.54
410.502.932.93
424.523.323.32
438.553.713.71
452.584.104.10
466.604.494.49
480.634.884.88
494.665.275.27
508.685.665.66
430.493.193.19
444.513.583.58
458.543.973.97
472.574.364.36
486.594.754.75
500.625.145.14
514.655.535.53
528.675.925.92
542.706.316.31
556.736.706.70
570.767.097.09
444.513.503.50
458.543.893.89
472.574.284.28
486.594.674.67
500.625.065.06
514.655.455.45
528.675.845.84
542.706.236.23
556.736.626.62
570.767.017.01
584.787.407.40
509.383.953.95
523.414.344.34
537.444.734.73
551.465.125.12
565.495.515.51
579.525.905.90
593.546.296.29
607.576.686.68
621.607.077.07
635.627.467.46
649.657.857.85
565.615.165.16
488.523.313.31
562.603.393.39
489.513.493.49