Basic Information
ID: ALA2061901
Type: Binding
Description: Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 mins by Amplite fluorimetric assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: JM109 (DE3)
Target: Glucose-6-phosphate 1-dehydrogenase(ALA5347)
Document: ALA2057131
Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 mins by Amplite fluorimetric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2061901
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.45 | 3.96 | 3.96 |
| 288.43 | 3.88 | 3.88 |
| 318.50 | 4.60 | 4.60 |
| 316.49 | 4.52 | 4.52 |
| 290.45 | 3.96 | 3.96 |
| 369.34 | 4.33 | 4.33 |
| 302.46 | 4.08 | 4.08 |
| 367.33 | 4.25 | 4.25 |
| 334.50 | 3.57 | 3.57 |
| 332.48 | 3.73 | 3.73 |
| 332.48 | 3.49 | 3.49 |
| 289.46 | 3.93 | 3.93 |
| 331.50 | 4.10 | 4.10 |
| 332.49 | 3.64 | 3.64 |
| 346.51 | 3.90 | 3.90 |
| 360.54 | 4.29 | 4.29 |
| 388.60 | 5.07 | 5.07 |
| 360.54 | 4.24 | 4.24 |
| 347.50 | 4.32 | 4.32 |
| 367.56 | 3.52 | 3.52 |
| 381.58 | 3.91 | 3.91 |
| 429.63 | 4.95 | 4.95 |
| 368.54 | 2.76 | 2.76 |
| 318.50 | 4.60 | 4.60 |
| 317.52 | 4.56 | 4.56 |
| 359.55 | 4.74 | 4.74 |
| 360.54 | 4.27 | 4.27 |
| 388.60 | 4.87 | 4.87 |
| 375.55 | 4.96 | 4.96 |
| 395.61 | 4.15 | 4.15 |
| 409.64 | 4.54 | 4.54 |
| 457.68 | 5.58 | 5.58 |
| 396.60 | 3.40 | 3.40 |
| 424.65 | 4.00 | 4.00 |
| 325.92 | 3.93 | 3.93 |
| 360.54 | 4.29 | 4.29 |
| 367.56 | 3.52 | 3.52 |
| 368.54 | 2.76 | 2.76 |
| 404.60 | 3.89 | 3.89 |
| 391.55 | 3.93 | 3.93 |
| 411.61 | 3.12 | 3.12 |
| 412.60 | 2.37 | 2.37 |
| 332.53 | 4.99 | 4.99 |
| 304.47 | 4.16 | 4.16 |
| 318.50 | 4.55 | 4.55 |
| 348.53 | 4.36 | 4.36 |
| 304.43 | 2.85 | 2.85 |
| 305.46 | 4.22 | 4.22 |
| 316.49 | 4.47 | 4.47 |
| 334.50 | 3.57 | 3.57 |
| 376.54 | 4.14 | 4.14 |
| 352.95 | 4.81 | 4.81 |
| 397.40 | 4.97 | 4.97 |
| 333.52 | 4.86 | 4.86 |
| 274.45 | 4.99 | 4.99 |
| 332.48 | 3.77 | 3.77 |
| 348.48 | 2.75 | 2.75 |
| 350.50 | 2.68 | 2.68 |
| 348.48 | 2.89 | 2.89 |