Assay Report Card

Basic Information

ID: ALA2066208

Type: Binding

Description: Inhibition of SMO expressed in mouse C3H10T1/2 cells assessed as down-regulation of Gli1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to oxysterol

Organism: Homo sapiens

Cell type: C3H 10T1/2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
384.657.627.62
396.667.647.64
384.657.627.62
418.665.785.78
366.638.428.42
390.707.867.86
266.475.035.03
264.455.235.23
248.455.985.98
212.332.192.19
278.485.055.05
154.211.011.01
330.514.794.79
330.514.794.79