Basic Information
ID: ALA2067457
Type: Binding
Description: Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate preincubated with compound for 15 mins measured after 10 mins by HTRF assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA2067457
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.45 | 3.01 | 3.01 |
| 354.38 | 3.60 | 3.60 |
| 364.44 | 4.11 | 4.11 |
| 311.35 | 1.07 | 1.07 |
| 325.37 | 1.08 | 1.08 |
| 329.33 | 1.21 | 1.21 |
| 343.36 | 1.22 | 1.22 |
| 343.36 | 1.22 | 1.22 |
| 343.36 | 1.22 | 1.22 |
| 390.24 | 1.84 | 1.84 |
| 345.79 | 1.73 | 1.73 |
| 325.37 | 1.38 | 1.38 |
| 341.37 | 1.08 | 1.08 |
| 379.34 | 2.09 | 2.09 |
| 339.40 | 1.57 | 1.57 |
| 369.40 | 2.02 | 2.02 |
| 387.42 | 1.33 | 1.33 |
| 393.49 | 3.05 | 3.05 |
| 387.44 | 2.54 | 2.54 |
| 401.47 | 2.60 | 2.60 |
| 387.44 | 2.74 | 2.74 |
| 401.47 | 2.75 | 2.75 |
| 401.47 | 2.75 | 2.75 |
| 401.47 | 2.75 | 2.75 |
| 401.47 | 2.75 | 2.75 |
| 330.32 | 1.48 | 1.48 |
| 330.32 | 1.48 | 1.48 |
| 330.32 | 1.48 | 1.48 |
| 330.32 | 1.48 | 1.48 |
| 326.36 | 1.65 | 1.65 |
| 326.36 | 1.65 | 1.65 |
| 326.36 | 1.65 | 1.65 |
| 391.23 | 2.10 | 2.10 |
| 388.43 | 3.01 | 3.01 |
| 388.43 | 3.01 | 3.01 |
| 394.46 | 3.07 | 3.07 |
| 389.42 | 2.40 | 2.40 |
| 389.42 | 2.40 | 2.40 |
| 389.42 | 2.40 | 2.40 |
| 406.42 | 3.14 | 3.14 |
| 312.33 | 1.34 | 1.34 |
| 314.35 | 0.79 | 0.79 |