Basic Information
ID: ALA2067458
Type: Binding
Description: Inhibition of N-terminus poly-His tagged human PI3Kgamma expressed in baculovirus infected insect sf9 cells using PI(4,5)P2 as substrate preincubated with compound for 15 mins measured after 10 mins by HTRF assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA2067458
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.45 | 3.01 | 3.01 |
| 354.38 | 3.60 | 3.60 |
| 364.44 | 4.11 | 4.11 |
| 311.35 | 1.07 | 1.07 |
| 325.37 | 1.08 | 1.08 |
| 329.33 | 1.21 | 1.21 |
| 343.36 | 1.22 | 1.22 |
| 343.36 | 1.22 | 1.22 |
| 343.36 | 1.22 | 1.22 |
| 390.24 | 1.84 | 1.84 |
| 345.79 | 1.73 | 1.73 |
| 325.37 | 1.38 | 1.38 |
| 341.37 | 1.08 | 1.08 |
| 379.34 | 2.09 | 2.09 |
| 339.40 | 1.57 | 1.57 |
| 369.40 | 2.02 | 2.02 |
| 387.42 | 1.33 | 1.33 |
| 393.49 | 3.05 | 3.05 |
| 387.44 | 2.54 | 2.54 |
| 401.47 | 2.60 | 2.60 |
| 387.44 | 2.74 | 2.74 |
| 401.47 | 2.75 | 2.75 |
| 401.47 | 2.75 | 2.75 |
| 401.47 | 2.75 | 2.75 |
| 401.47 | 2.75 | 2.75 |
| 330.32 | 1.48 | 1.48 |
| 330.32 | 1.48 | 1.48 |
| 330.32 | 1.48 | 1.48 |
| 330.32 | 1.48 | 1.48 |
| 326.36 | 1.65 | 1.65 |
| 326.36 | 1.65 | 1.65 |
| 326.36 | 1.65 | 1.65 |
| 391.23 | 2.10 | 2.10 |
| 388.43 | 3.01 | 3.01 |
| 388.43 | 3.01 | 3.01 |
| 394.46 | 3.07 | 3.07 |
| 389.42 | 2.40 | 2.40 |
| 389.42 | 2.40 | 2.40 |
| 389.42 | 2.40 | 2.40 |
| 406.42 | 3.14 | 3.14 |
| 312.33 | 1.34 | 1.34 |
| 314.35 | 0.79 | 0.79 |