Basic Information
ID: ALA2071936
Type: Binding
Description: Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Voltage-gated potassium channel subunit Kv7.1(ALA1866)
Document: ALA2069205
Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2071936
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.58 | 4.00 | 4.00 |
| 457.58 | 4.00 | 4.00 |
| 457.58 | 4.00 | 4.00 |
| 471.60 | 4.31 | 4.31 |
| 471.60 | 4.31 | 4.31 |
| 471.60 | 4.31 | 4.31 |
| 499.66 | 4.95 | 4.95 |
| 499.66 | 5.12 | 5.12 |
| 513.69 | 5.30 | 5.30 |
| 525.57 | 5.02 | 5.02 |
| 525.57 | 5.02 | 5.02 |
| 525.57 | 5.02 | 5.02 |
| 487.60 | 4.01 | 4.01 |
| 487.60 | 4.01 | 4.01 |
| 501.59 | 3.73 | 3.73 |
| 482.59 | 3.87 | 3.87 |
| 482.59 | 3.87 | 3.87 |
| 482.59 | 3.87 | 3.87 |
| 475.57 | 4.14 | 4.14 |
| 475.57 | 4.14 | 4.14 |
| 492.02 | 4.65 | 4.65 |
| 492.02 | 4.65 | 4.65 |
| 492.02 | 4.65 | 4.65 |
| 526.47 | 5.31 | 5.31 |
| 510.01 | 4.79 | 4.79 |
| 510.01 | 4.79 | 4.79 |
| 489.59 | 4.45 | 4.45 |
| 506.05 | 4.80 | 4.80 |
| 506.05 | 4.80 | 4.80 |
| 508.63 | 4.55 | 4.55 |
| 458.57 | 3.40 | 3.40 |
| 461.57 | 2.73 | 2.73 |
| 472.59 | 3.70 | 3.70 |
| 439.51 | 4.59 | 4.59 |
| 421.52 | 4.45 | 4.45 |
| 451.55 | 4.46 | 4.46 |
| 485.63 | 4.70 | 4.70 |
| 457.58 | 3.92 | 3.92 |
| 443.55 | 3.53 | 3.53 |
| 473.58 | 3.16 | 3.16 |
| 489.64 | 3.87 | 3.87 |
| 472.59 | 2.73 | 2.73 |
| 471.60 | 4.17 | 4.17 |
| 471.60 | 4.17 | 4.17 |
| 431.54 | 3.43 | 3.43 |
| 473.62 | 4.46 | 4.46 |
| 459.59 | 4.07 | 4.07 |
| 431.54 | 3.43 | 3.43 |
| 483.66 | 5.42 | 5.42 |
| 441.58 | 4.30 | 4.30 |
| 459.57 | 4.44 | 4.44 |
| 455.61 | 4.61 | 4.61 |
| 486.58 | 4.21 | 4.21 |
| 476.02 | 4.95 | 4.95 |
| 365.48 | 2.63 | 2.63 |
| 415.54 | 3.79 | 3.79 |
| 481.60 | 5.05 | 5.05 |
| 525.57 | 5.20 | 5.20 |
| 471.60 | 4.31 | 4.31 |
| 472.59 | 3.70 | 3.70 |
| 481.60 | 5.05 | 5.05 |
| 482.59 | 4.44 | 4.44 |
| 493.01 | 4.05 | 4.05 |
| 595.54 | 5.79 | 5.79 |