Basic Information
ID: ALA2071968
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as high signal/noise ratio (S/N of >100) by measuring GSH adduct formation at 100 uM after 90 mins by HPLC-MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2071968
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.36 | 4.83 | 4.83 |
| 252.35 | 0.60 | 0.60 |
| 393.47 | 4.51 | 4.51 |
| 182.19 | 0.07 | 0.07 |
| 308.38 | 3.79 | 3.79 |
| 334.33 | -1.65 | -1.65 |
| 236.27 | 3.39 | 3.39 |
| 151.16 | 1.35 | 1.35 |
| 383.47 | -0.31 | -0.31 |
| 356.49 | 3.66 | 3.66 |
| 277.41 | 4.17 | 4.17 |
| 272.39 | 3.61 | 3.61 |
| 296.41 | 3.61 | 3.61 |
| 303.83 | 4.19 | 4.19 |
| 199.16 | -1.10 | -1.10 |
| 318.34 | 3.20 | 3.20 |
| 246.31 | -0.28 | -0.28 |
| 435.44 | -1.17 | -1.17 |
| 588.56 | 1.34 | 1.34 |
| 554.59 | -1.20 | -1.20 |
| 187.29 | 2.18 | 2.18 |
| 418.57 | 4.59 | 4.59 |
| 181.22 | 0.57 | 0.57 |
| 324.38 | 3.49 | 3.49 |
| 357.49 | 3.34 | 3.34 |
| 374.91 | 4.04 | 4.04 |
| 324.42 | 3.17 | 3.17 |
| 152.18 | 0.64 | 0.64 |
| 822.95 | 4.34 | 4.34 |
| 345.42 | 2.90 | 2.90 |
| 434.50 | 2.27 | 2.27 |
| 170.24 | 1.38 | 1.38 |
| 277.27 | 1.15 | 1.15 |
| 186.24 | 1.56 | 1.56 |
| 813.98 | 3.62 | 3.62 |
| 314.41 | 1.46 | 1.46 |