Basic Information
ID: ALA2071975
Type: Functional
Description: Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Zn2+-induced intracellular calcium flux by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2071975
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.35 | 3.23 | 3.23 |
| 281.36 | 3.32 | 3.32 |
| 299.35 | 3.46 | 3.46 |
| 315.80 | 3.98 | 3.98 |
| 360.25 | 4.09 | 4.09 |
| 315.80 | 3.98 | 3.98 |
| 350.25 | 4.63 | 4.63 |
| 306.37 | 3.20 | 3.20 |
| 359.45 | 2.73 | 2.73 |
| 296.37 | 2.91 | 2.91 |
| 376.50 | 4.50 | 4.50 |
| 340.81 | 3.85 | 3.85 |
| 336.39 | 3.20 | 3.20 |
| 375.25 | 4.50 | 4.50 |
| 358.80 | 3.99 | 3.99 |
| 358.80 | 3.99 | 3.99 |
| 408.81 | 4.87 | 4.87 |
| 374.36 | 4.21 | 4.21 |
| 353.42 | 3.48 | 3.48 |
| 387.44 | 4.16 | 4.16 |
| 353.42 | 3.62 | 3.62 |
| 359.43 | 3.69 | 3.69 |
| 356.51 | 5.02 | 5.02 |
| 339.37 | 3.73 | 3.73 |
| 335.41 | 3.26 | 3.26 |
| 361.45 | 3.53 | 3.53 |
| 315.42 | 3.21 | 3.21 |
| 324.85 | 3.99 | 3.99 |
| 310.83 | 3.65 | 3.65 |
| 311.81 | 4.07 | 4.07 |
| 302.37 | 3.29 | 3.29 |
| 320.36 | 3.43 | 3.43 |
| 312.80 | 3.47 | 3.47 |
| 329.83 | 4.37 | 4.37 |
| 313.78 | 3.73 | 3.73 |
| 315.80 | 4.12 | 4.12 |
| 329.83 | 4.37 | 4.37 |
| 374.87 | 4.32 | 4.32 |
| 313.78 | 3.88 | 3.88 |
| 273.72 | 2.95 | 2.95 |
| 385.44 | 4.14 | 4.14 |
| 437.42 | 3.83 | 3.83 |
| 428.79 | 4.90 | 4.90 |