Assay Report Card

Basic Information

ID: ALA2072611

Type: Binding

Description: Inhibition of human NaV1.2 expressed in HEK293 cells at 10 uM using sodium currents elicited through depolarizing step from holding potential of -100 mV to +10 mV for 25 ms at 15 s intervals by whole cell patch clamp method

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
252.271.771.77
308.813.743.74
529.064.134.13