Basic Information
ID: ALA2073152
Type: Binding
Description: Inhibition of VDR-LBD expressed in human HEK293T cells co-expressing GAL4-DBD assessed as inhibition of 1,25-(OH)2D3-induced transcription at 62.5 uM after 24 hrs by FRET based GeneBLAzer assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Vitamin D receptor(ALA1977)
Document: ALA2069300
Inhibition of VDR-LBD expressed in human HEK293T cells co-expressing GAL4-DBD assessed as inhibition of 1,25-(OH)2D3-induced transcription at 62.5 uM after 24 hrs by FRET based GeneBLAzer assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2073152
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.32 | 1.91 | 1.91 |
| 363.35 | 1.62 | 1.62 |
| 297.41 | 2.05 | 2.05 |
| 275.35 | 4.50 | 4.50 |
| 343.43 | 5.08 | 5.08 |
| 327.43 | 5.38 | 5.38 |
| 343.43 | 5.08 | 5.08 |
| 392.30 | 5.84 | 5.84 |
| 392.30 | 5.84 | 5.84 |
| 331.39 | 5.21 | 5.21 |
| 347.85 | 5.73 | 5.73 |
| 331.39 | 5.21 | 5.21 |
| 291.73 | 3.32 | 3.32 |
| 286.33 | 4.05 | 4.05 |
| 305.16 | 4.20 | 4.20 |
| 388.88 | 4.54 | 4.54 |
| 293.39 | 1.99 | 1.99 |