Basic Information
ID: ALA2073526
Type: Binding
Description: Inhibition of IKKbeta in human HeLa cells assessed as inhibition of TPA-induced NFkappaB activation at 10 uM incubated for 1 hr prior to TPA-challenge measured after 8 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA2073526
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.36 | 2.38 | 2.38 |
| 535.69 | 5.56 | 5.56 |
| 588.76 | 5.00 | 5.00 |
| 588.76 | 5.00 | 5.00 |
| 588.76 | 5.00 | 5.00 |
| 559.71 | 5.85 | 5.85 |
| 573.74 | 6.24 | 6.24 |
| 573.74 | 6.24 | 6.24 |
| 547.70 | 5.70 | 5.70 |
| 547.70 | 5.70 | 5.70 |
| 559.71 | 5.85 | 5.85 |
| 553.15 | 7.65 | 7.65 |
| 561.73 | 6.09 | 6.09 |
| 561.73 | 6.09 | 6.09 |
| 535.69 | 5.56 | 5.56 |