Basic Information
ID: ALA2073576
Type: Binding
Description: Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA2073576
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 328.37 | 2.54 | 2.54 |
| 386.40 | 2.31 | 2.31 |
| 386.40 | 2.31 | 2.31 |
| 416.43 | 2.32 | 2.32 |
| 414.46 | 3.09 | 3.09 |
| 400.43 | 2.70 | 2.70 |
| 372.38 | 2.01 | 2.01 |
| 404.39 | 2.45 | 2.45 |
| 420.85 | 2.97 | 2.97 |
| 465.30 | 3.08 | 3.08 |
| 404.39 | 2.45 | 2.45 |
| 420.85 | 2.97 | 2.97 |
| 465.30 | 3.08 | 3.08 |
| 434.88 | 3.36 | 3.36 |
| 479.33 | 3.47 | 3.47 |
| 370.41 | 2.61 | 2.61 |
| 424.38 | 3.32 | 3.32 |
| 374.37 | 2.44 | 2.44 |
| 390.82 | 2.96 | 2.96 |
| 435.27 | 3.07 | 3.07 |
| 423.24 | 3.20 | 3.20 |
| 369.35 | 2.31 | 2.31 |
| 400.43 | 2.62 | 2.62 |
| 465.30 | 3.08 | 3.08 |
| 451.27 | 3.03 | 3.03 |
| 450.33 | 3.37 | 3.37 |
| 450.33 | 3.37 | 3.37 |
| 505.41 | 3.06 | 3.06 |
| 476.37 | 3.90 | 3.90 |
| 476.37 | 3.90 | 3.90 |
| 492.37 | 3.14 | 3.14 |
| 526.41 | 2.84 | 2.84 |
| 540.44 | 2.54 | 2.54 |
| 408.25 | 2.70 | 2.70 |
| 493.36 | 2.54 | 2.54 |
| 491.39 | 3.69 | 3.69 |
| 458.31 | 3.85 | 3.85 |
| 458.31 | 3.85 | 3.85 |
| 458.31 | 3.85 | 3.85 |
| 461.32 | 3.19 | 3.19 |
| 473.33 | 3.49 | 3.49 |
| 474.32 | 2.88 | 2.88 |
| 475.30 | 2.28 | 2.28 |
| 474.32 | 2.88 | 2.88 |
| 473.33 | 3.49 | 3.49 |
| 506.40 | 3.53 | 3.53 |
| 520.42 | 3.92 | 3.92 |
| 487.35 | 3.88 | 3.88 |
| 501.38 | 4.27 | 4.27 |