Basic Information
ID: ALA2073616
Type: Binding
Description: Inhibition of PDE8B expressed in Sf9 insect cells
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA2073616
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.61 | 5.03 | 5.03 |
| 373.38 | 1.78 | 1.78 |
| 302.26 | 1.39 | 1.39 |
| 288.23 | 1.00 | 1.00 |
| 234.26 | 0.37 | 0.37 |
| 248.29 | 0.68 | 0.68 |
| 274.33 | 1.25 | 1.25 |
| 278.32 | 0.52 | 0.52 |
| 354.44 | 0.70 | 0.70 |
| 310.36 | 2.04 | 2.04 |
| 316.41 | 2.42 | 2.42 |
| 260.30 | 0.86 | 0.86 |
| 274.33 | 1.11 | 1.11 |
| 274.33 | 1.11 | 1.11 |
| 300.75 | 2.38 | 2.38 |
| 296.34 | 1.33 | 1.33 |
| 298.35 | 1.51 | 1.51 |
| 301.38 | 1.75 | 1.75 |
| 259.31 | 1.46 | 1.46 |
| 259.31 | 1.46 | 1.46 |
| 365.45 | 1.56 | 1.56 |
| 356.46 | 1.66 | 1.66 |
| 365.45 | 1.70 | 1.70 |
| 363.47 | 2.59 | 2.59 |
| 365.44 | 1.58 | 1.58 |
| 394.36 | 1.12 | 1.12 |
| 372.46 | 1.04 | 1.04 |
| 367.42 | 0.37 | 0.37 |
| 346.42 | 0.47 | 0.47 |
| 374.47 | 1.03 | 1.03 |
| 375.38 | 1.29 | 1.29 |
| 386.38 | 2.40 | 2.40 |
| 393.37 | 2.82 | 2.82 |
| 262.32 | 0.77 | 0.77 |
| 358.37 | 2.88 | 2.88 |
| 407.40 | 2.99 | 2.99 |
| 382.35 | 1.73 | 1.73 |
| 388.42 | 2.73 | 2.73 |
| 370.38 | 3.16 | 3.16 |
| 408.38 | 2.91 | 2.91 |
| 394.36 | 2.13 | 2.13 |
| 359.36 | 1.39 | 1.39 |
| 382.35 | 2.67 | 2.67 |
| 382.35 | 2.93 | 2.93 |
| 392.39 | 3.34 | 3.34 |
| 410.38 | 3.21 | 3.21 |
| 360.34 | 1.87 | 1.87 |
| 379.35 | 2.43 | 2.43 |
| 404.40 | 3.00 | 3.00 |
| 393.37 | 2.47 | 2.47 |
| 408.38 | 3.04 | 3.04 |
| 384.41 | 3.55 | 3.55 |
| 302.26 | 1.46 | 1.46 |
| 328.30 | 1.99 | 1.99 |
| 372.35 | 2.01 | 2.01 |
| 373.38 | 1.78 | 1.78 |
| 360.34 | 1.87 | 1.87 |
| 360.30 | 1.00 | 1.00 |
| 406.41 | 3.46 | 3.46 |
| 384.41 | 3.41 | 3.41 |
| 281.28 | 0.73 | 0.73 |
| 299.29 | -0.04 | -0.04 |
| 276.34 | 1.33 | 1.33 |
| 316.39 | 2.10 | 2.10 |
| 306.33 | 0.09 | 0.09 |
| 300.32 | 1.63 | 1.63 |
| 311.35 | 1.43 | 1.43 |
| 262.32 | 0.93 | 0.93 |
| 288.36 | 1.64 | 1.64 |
| 330.42 | 2.02 | 2.02 |
| 330.42 | 2.02 | 2.02 |
| 288.36 | 1.33 | 1.33 |
| 290.37 | 1.72 | 1.72 |
| 304.40 | 1.96 | 1.96 |
| 324.39 | 1.96 | 1.96 |
| 290.37 | 1.57 | 1.57 |
| 356.45 | 2.66 | 2.66 |
| 294.38 | 1.24 | 1.24 |
| 306.33 | 0.44 | 0.44 |
| 264.29 | -0.14 | -0.14 |
| 314.35 | 0.62 | 0.62 |
| 292.30 | 0.00 | 0.00 |
| 331.40 | 1.80 | 1.80 |
| 315.34 | 1.34 | 1.34 |
| 273.30 | 0.44 | 0.44 |
| 291.31 | -0.60 | -0.60 |
| 304.35 | 1.22 | 1.22 |
| 344.35 | 1.70 | 1.70 |
| 264.29 | 0.13 | 0.13 |
| 322.37 | 1.99 | 1.99 |
| 284.33 | 0.66 | 0.66 |
| 320.36 | 1.69 | 1.69 |
| 333.36 | 1.51 | 1.51 |
| 301.38 | 1.69 | 1.69 |
| 308.35 | 1.66 | 1.66 |
| 319.37 | 2.77 | 2.77 |
| 333.36 | 1.31 | 1.31 |
| 334.34 | 0.97 | 0.97 |
| 286.38 | 2.82 | 2.82 |
| 316.39 | 2.21 | 2.21 |
| 335.42 | 1.74 | 1.74 |
| 309.38 | 2.19 | 2.19 |
| 326.39 | 1.75 | 1.75 |
| 321.35 | 1.08 | 1.08 |
| 334.31 | 2.75 | 2.75 |
| 345.41 | 0.71 | 0.71 |
| 350.43 | 2.43 | 2.43 |
| 324.34 | 1.50 | 1.50 |
| 373.46 | 2.47 | 2.47 |
| 320.36 | 1.69 | 1.69 |
| 312.38 | 1.75 | 1.75 |