Basic Information
ID: ALA2089548
Type: Functional
Description: Antagonist activity at glucocorticoid receptor in rat hepatocytes assessed as inhibition of dexamethasone-induced trypsine aminotransferase expression incubated for 30 mins prior to dexamethasone-induction measured after 4 hrs by reporter gene assay
Organism: Rattus norvegicus
Cell type: Hepatocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA2089548
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.48 | 6.69 | 6.69 |
| 409.49 | 6.38 | 6.38 |
| 423.51 | 6.31 | 6.31 |
| 581.30 | 7.84 | 7.84 |
| 599.29 | 7.98 | 7.98 |
| 617.28 | 8.12 | 8.12 |
| 600.62 | 6.25 | 6.25 |
| 576.28 | 7.30 | 7.30 |
| 635.27 | 8.26 | 8.26 |
| 653.26 | 8.39 | 8.39 |
| 651.73 | 8.77 | 8.77 |
| 686.17 | 9.42 | 9.42 |
| 696.18 | 8.88 | 8.88 |
| 775.08 | 9.64 | 9.64 |
| 631.31 | 8.42 | 8.42 |
| 645.34 | 8.73 | 8.73 |
| 647.31 | 8.12 | 8.12 |
| 677.34 | 8.13 | 8.13 |
| 685.28 | 9.13 | 9.13 |
| 753.28 | 10.15 | 10.15 |