Basic Information
ID: ALA2091093
Type: Binding
Description: Inhibition of human ABCB1 expressed in mouse L5178 cells assessed as 50% inhibition of cell proliferation at compound-doxorubicin ratio of 81.5:1 after 48 hrs by MTT assay
Organism: Homo sapiens
Cell type: L5178
Activity Charts
Bioactivity
Activity Types for Assay ALA2091093
FICI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.64 | 2.74 | 2.74 |
| 464.64 | 2.74 | 2.74 |
| 496.64 | 0.82 | 0.82 |
| 478.63 | 1.77 | 1.77 |
| 496.64 | 0.82 | 0.82 |
| 464.64 | 2.88 | 2.88 |
| 448.64 | 3.77 | 3.77 |
| 480.64 | 1.85 | 1.85 |
| 626.78 | 0.71 | 0.71 |
| 512.64 | -0.06 | -0.06 |
| 480.64 | 1.85 | 1.85 |
| 480.64 | 1.85 | 1.85 |
| 480.64 | 2.00 | 2.00 |
| 516.63 | 2.16 | 2.16 |
| 360.45 | 1.70 | 1.70 |
| 462.63 | 2.90 | 2.90 |
| 522.68 | 2.42 | 2.42 |
| 506.68 | 3.45 | 3.45 |
| 664.79 | 3.25 | 3.25 |
| 504.71 | 4.68 | 4.68 |
| 548.76 | 4.29 | 4.29 |
| 536.71 | 2.77 | 2.77 |