Basic Information
ID: ALA2091095
Type: Binding
Description: Inhibition of human ABCB1 expressed in mouse L5178 cells assessed as 75% inhibition of cell proliferation at compound-doxorubicin ratio of 20.4:1 after 48 hrs by MTT assay
Organism: Homo sapiens
Cell type: L5178
Activity Charts
Bioactivity
Activity Types for Assay ALA2091095
FICI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.64 | 1.85 | 1.85 |
| 496.64 | 0.97 | 0.97 |
| 480.64 | 1.71 | 1.71 |
| 480.64 | 1.85 | 1.85 |
| 462.63 | 2.66 | 2.66 |
| 532.72 | 4.91 | 4.91 |
| 648.79 | 4.14 | 4.14 |
| 574.76 | 5.48 | 5.48 |
| 520.71 | 3.65 | 3.65 |
| 576.77 | 4.42 | 4.42 |
| 576.77 | 4.42 | 4.42 |
| 504.71 | 4.68 | 4.68 |
| 520.71 | 3.51 | 3.51 |
| 616.84 | 6.22 | 6.22 |
| 560.77 | 5.31 | 5.31 |
| 542.76 | 6.26 | 6.26 |
| 560.77 | 5.45 | 5.45 |
| 588.83 | 6.09 | 6.09 |