Basic Information
ID: ALA2091473
Type: Functional
Description: Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for 10 mins by FLIPR assay relative to nicotine
Organism: Rattus norvegicus
Cell type: GH4-C1
Activity Charts
Bioactivity
Activity Types for Assay ALA2091473
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 146.21 | 0.26 | 0.26 |
| 413.52 | 2.75 | 2.75 |
| 427.55 | 3.06 | 3.06 |
| 427.55 | 2.99 | 2.99 |
| 413.52 | 2.75 | 2.75 |
| 288.35 | 1.28 | 1.28 |
| 370.92 | 5.60 | 5.60 |
| 385.94 | 5.39 | 5.39 |
| 360.89 | 4.32 | 4.32 |
| 374.92 | 4.34 | 4.34 |
| 377.94 | 5.06 | 5.06 |
| 378.93 | 4.45 | 4.45 |
| 361.87 | 4.59 | 4.59 |
| 356.47 | 3.68 | 3.68 |
| 356.47 | 3.68 | 3.68 |
| 356.47 | 3.68 | 3.68 |
| 370.50 | 3.99 | 3.99 |
| 344.43 | 3.81 | 3.81 |
| 405.34 | 4.43 | 4.43 |
| 327.43 | 3.07 | 3.07 |
| 394.44 | 4.69 | 4.69 |
| 316.41 | 3.26 | 3.26 |
| 370.50 | 3.93 | 3.93 |
| 358.44 | 2.53 | 2.53 |
| 371.44 | 1.63 | 1.63 |
| 399.50 | 2.39 | 2.39 |
| 370.50 | 4.07 | 4.07 |
| 372.47 | 2.92 | 2.92 |
| 371.49 | 2.49 | 2.49 |
| 385.47 | 2.02 | 2.02 |