Basic Information
ID: ALA2091475
Type: Functional
Description: Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec for 1 min followed by every 3 secs for 3 mins by FLIPR assay
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA2091475
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.52 | 2.75 | 2.75 |
| 427.55 | 2.99 | 2.99 |
| 356.47 | 3.68 | 3.68 |
| 356.47 | 3.68 | 3.68 |
| 344.43 | 3.81 | 3.81 |
| 405.34 | 4.43 | 4.43 |
| 358.44 | 2.53 | 2.53 |
| 370.50 | 4.07 | 4.07 |
| 372.47 | 2.92 | 2.92 |