Basic Information
ID: ALA2091978
Type: Binding
Description: Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 0.25 uM icilin-stimulated increase in intracellular Ca2+ levels
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2091978
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 150.22 | 2.82 | 2.82 |
| 299.37 | 4.74 | 4.74 |
| 268.36 | 4.65 | 4.65 |
| 310.44 | 5.64 | 5.64 |
| 330.43 | 6.00 | 6.00 |
| 284.36 | 4.35 | 4.35 |
| 344.45 | 5.93 | 5.93 |
| 310.44 | 5.64 | 5.64 |
| 330.43 | 6.00 | 6.00 |
| 288.77 | 4.99 | 4.99 |
| 284.36 | 4.35 | 4.35 |
| 309.45 | 5.67 | 5.67 |
| 321.34 | 5.39 | 5.39 |
| 329.44 | 6.04 | 6.04 |
| 287.79 | 5.02 | 5.02 |
| 283.37 | 4.38 | 4.38 |
| 281.40 | 4.09 | 4.09 |
| 426.56 | 6.15 | 6.15 |
| 309.45 | 5.67 | 5.67 |
| 329.44 | 6.04 | 6.04 |
| 283.37 | 4.38 | 4.38 |
| 343.47 | 5.97 | 5.97 |
| 393.27 | 4.90 | 4.90 |
| 351.53 | 6.64 | 6.64 |
| 325.45 | 6.03 | 6.03 |
| 337.34 | 5.75 | 5.75 |
| 345.44 | 6.40 | 6.40 |
| 345.44 | 6.40 | 6.40 |
| 299.37 | 4.74 | 4.74 |
| 325.45 | 6.03 | 6.03 |
| 345.44 | 6.40 | 6.40 |
| 324.47 | 6.06 | 6.06 |
| 344.46 | 6.43 | 6.43 |
| 298.39 | 4.77 | 4.77 |
| 185.70 | 2.70 | 2.70 |